Corneal Transplant

Aris carries out surgery and provides treatment for a range of corneal conditions including: 

  • Fuchs endothelial dystrophy
  • Corneal transplantation surgery: Descemets stripping endothelial keratoplasty (DSEK), deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) 
  • Recurrent corneal erosion syndrome
  • Pterygium
  • Corneal infection and corneal scars 

Corneal transplantation surgery DSEK, DALK and PK

Why different types of corneal transplantation?

With modern technology and the evolution of techniques we are fortunate to have a variety of corneal transplantation procedures available, allowing us to address the underlying condition with the procedure that is most appropriate, safest and provides the best outcome. 

What is penetrating keratoplasty? 

 Penetrating keratoplasty (PK) involves replacing all the layers of the affected cornea with a full thickness transplant. It is usually carried out when the condition is affecting more than one layers or the full thickness of the cornea, e.g in very advanced keratoconus or following trauma. 

What is Descemets stripping endothelial keratoplasty? 



Endothelial keratoplasty, including Descemets stripping endothelial keratoplasty (DSEK), is currently the gold standard in the management of Fuchs endothelial dystrophy and bullous keratopathy. It involves the selective replacement of the dysfunctional inner layer of the cornea with a thin layer of transplant cornea that has healthy endothelial cells. 

DSEK has several advantages over full thickness penetrating keratoplasty (PK) including:

  • keyhole surgery allows faster improvement in vision

  • surgery is carried out under local anaesthetic and in less than an hour; the risks of a general anaesthetic are thus avoided

  • reduced risk of serious complications

  • reduced risk of needing high-power glasses or contact lenses after surgery

What is deep anterior lamellar keratoplasty?

In deep anterior lamellar keratoplasty (DALK)​ 90% of the affected cornea is replaced with 

the transplant cornea, leaving you with your own endothelial layer. The commonest indications for DALK are keratoconus and corneal scars. 


DALK has several advantages over full thickness penetrating keratoplasty (PK) including:

  • reduced risk of graft rejection

  • sutures can be removed sooner

  • reduced risk of serious complications

  • faster visual recovery

How to proceed?

  • If you interested in a consultation or surgery, call or send us a message

  • Select a hospital for consultation: Wessex Nuffield, Guildford Nuffield, Southampton Spire or Southampton General Hospital

  • At your consultation your symptoms and needs will be ascertained, you will have a detailed eye examination and scans, and a surgical plan made to match your eyes and needs

  • Select a hospital for surgery, if required: Wessex Nuffield or Southampton General

  • Select a hospital for your follow-up consultation: Wessex Nuffield, Guildford Nuffield, Southampton Spire or Southampton General Hospital

Clinic Locations

Nuffield Health Wessex Hospital 

Nuffield Health Guildford Hospital

Southampton Spire Hospital

University Hospital Southampton NHS

Book an appointment or a free screening review for Laser Vision Correction.


Call 02381 812281

Leave a message

Aris Konstantopoulos MB ChB, MSc, FRCOphth, PhD

Consultant Eye Surgeon

Cataract, cornea and refractive surgery

Consultation clinics:

  • Nuffield Health Wessex Hospital, Eastleigh, SO53 2DW

  • Nuffield Health Guildford Hospital, Guildford, GU2 7RF

  • Southampton Spire Hospital, Southampton, SO16 6UY

  • University Hospital Southampton NHS FT, SO16 6YD


Mr Aris Konstantopoulos

Aris Vision Correction

Southampton Spire Hospital

Southampton, SO16 6UY

T: 02381 812281

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